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Geistlich Derma-Gide®

Expect Scientific Evidence*

In a chronic wound situation the physiological balance between matrix metalloproteinases (MMPs) and growth factors is disturbed. This is associated with inadequate cell migration and proliferation as well as matrix degradation,, which results in stalled healing.1,2 Geistlich Derma-Gide® supports the rebalancing of these factors.3 In vitro studies led to the discovery of the following clinically relevant characteristics:

  • Matrix Metalloproteinases (MMP) Activity
    Geistlich Derma-Gide® is shown to modulate MMP activity.
     
  • Growth Factor Binding and Preservation
    The Geistlich Derma-Gide® matrix maintains growth factors in an active state in situ, which is necessary for wound healing.
     
  • Cell Migration
    Geistlich Derma-Gide® provides optimal structure for cell migration and attachment.
     

 

 

References:

  1. Krishnaswamy et al. 2017
  2. Armstrong et al. 2002
  3. Data on file

* Performance in in vitro studies may not be representative of performance in humans.